Organic nitroso compounds
Medchemexpress LLC BUSPIRONE 50.0MG
Buspirone is an orally active 5-HT1A receptor agonist, and a dopamine D2 autoreceptorsant antagonist. Buspirone is an anxiolytic agent and can be used for the generalized anxiety disorder research.
Medchemexpress LLC 4-nitroso hydrochlorothiazide-13C,15N2,d2 | 63779-86-2 | 99.3% | C613CH5D2ClN215N2O5S2 | 100 UG
4-Nitroso hydrochlorothiazide-13C,15N2,d2 is an isotopically labeled compound, primarily used for research purposes. This compound serves as a tracer and an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. The incorporation of stable heavy isotopes like deuterium, 13C, and 15N into drug molecules is a common practice in drug development to facilitate quantitation and to study their pharmacokinetic and metabolic profiles, as deuteration can influence these aspects.
- Used as a tracer in research applications
- Functions as an internal standard for quantitative analysis
- Suitable for use with NMR, GC-MS, or LC-MS techniques
- Incorporates stable heavy isotopes for enhanced research capabilities
Medchemexpress LLC N-Nitroso-3-azabicyclo[3.3.0]octane-d4 | 1346604-35-0 | 95.0% | C7H8D4N2O | 100 MG
N-Nitroso-3-azabicyclo[3.3.0]octane-d4 is the deuterium labeled N-Nitroso-3-azabicyclo[3.3.0]octane. It is for research use only and not intended for human use. Deuterium labeled compounds can be used as tracers or internal standards for quantitative analysis by methods like NMR, GC-MS, or LC-MS. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC TANDSOPIRONE 50.0MG
Tandospirone /SM-3997/ is a potent and selective 5-HT1A receptor partial agonist with a Ki of 27 nM. Tandospirone has anxiolytic and antidepressant activities. Tandospirone can be used for the research of the central nervous system disorders and the underlying mechanisms.For research use only.
Medchemexpress LLC N-Nitroso-N-methylurea | 684-93-5 | 99.7% | 103.08 | 2 G
N-Nitroso-N-methylurea is a potent carcinogen, mutagen, and teratogen. It acts as a direct-acting alkylating agent that interacts with DNA, targeting multiple animal organs to cause various cancers and/or degenerative diseases. It is also a precursor in the synthesis of diazomethane.
- Potent carcinogen, mutagen, and teratogen
- Direct-acting alkylating agent that interacts with DNA
- Targets multiple animal organs to cause various cancers and/or degenerative diseases
- Precursor in the synthesis of diazomethane
- For research use only
Medchemexpress LLC N-Nitroso-N-methylurea | 684-93-5 | 103.08 | 5 G
N-Nitroso-N-methylurea is a potent carcinogen, mutagen, and teratogen. It functions as a direct-acting alkylating agent, interacting with DNA, and is known to target multiple animal organs, potentially leading to various cancers or degenerative diseases. This compound also serves as a precursor in the synthesis of diazomethane. It is a flammable solid intended for laboratory use in the manufacture of substances and is stable under recommended storage conditions.
- Functions as a direct-acting alkylating agent
- Interacts with DNA
- Targets multiple animal organs
- Leads to various cancers and/or degenerative diseases
- Precursor in the synthesis of diazomethane
- Used in animal modeling to construct tumor models
Medchemexpress LLC 4-nitroso hydrochlorothiazide-13C,15N2,d2 | 00-00-0 | MFCD34676448 | 99.3% | 331.73 g·mol⁻1 | C613CH5D2ClN215N2O5S2 | 5 MG
4-Nitroso hydrochlorothiazide-13C,15N2,d2 is an isotopically labeled analytical standard intended for use as an internal standard and tracer in mass spectrometry and quantitative assays. The material contains 13C, 15N, and deuterium labels (d2), is supplied as a high-purity solid in research-scale quantities, and is accompanied by manufacturer documentation (SDS and certificate of analysis) for laboratory use.
- Isotopically labeled with 13C, 15N2, and d2.
- High purity suitable for quantitative analysis (~99.3%).
- Suitable as an internal standard for mass spectrometry.
- Useful for method development and isotopic tracing studies.
- Supplied in small, research-scale quantities for analytical use.
- Documentation such as SDS and certificate of analysis available.
Medchemexpress LLC (R)-PR-924 | 1416709-79-9 | 98.5% | 618.72 | 50 MG
(R)-PR-924 is an isomer of PR-924, which can be used as an experimental control. PR-924 is a selective tripeptide epoxyketone immunoproteasome subunit LMP-7 inhibitor with an IC50 of 22 nM. It covalently modifies proteasomal N-terminal threonine active sites, inhibits growth, and triggers apoptosis in multiple myeloma (MM) cells, also exhibiting antitumor activities.
- Selective immunoproteasome subunit LMP-7 inhibitor.
- Covalently modifies proteasomal N-terminal threonine active sites.
- Inhibits growth in multiple myeloma (MM) cells.
- Triggers apoptosis in multiple myeloma (MM) cells.
- Exhibits antitumor activities.
- Can be used as an experimental control.
![Medchemexpress LLC N-nitroso-3-azabicyclo[3.3.0]octane-d4 | 1346604-35-0 | 95.0% | 144.21 g/mol | C7H8D4N2O | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000222594.png-250.jpg)
Medchemexpress LLC N-nitroso-3-azabicyclo[3.3.0]octane-d4 | 1346604-35-0 | 95.0% | 144.21 g/mol | C7H8D4N2O | 5 MG
N-Nitroso-3-azabicyclo[3.3.0]octane-d4 is the deuterium-labeled isotopologue of N-nitroso-3-azabicyclo[3.3.0]octane provided as a reference material for analytical and research applications. It is supplied as a solid for use as an internal standard in mass spectrometry and isotopic labeling studies; not for human or veterinary use.
- Deuterium-labeled internal standard for mass spectrometry.
- Suitable for quantitative and qualitative analytical methods.
- Provided with batch-specific certificate of analysis.
- Stable solid form suitable for recommended long-term storage.
- Intended for research use only.
Medchemexpress LLC (R)-PR-924 | 98.5% | 618.72 | 10 MG
(R)-PR-924 is an isomer of PR-924 used as an experimental control. PR-924 is a selective tripeptide epoxyketone immunoproteasome subunit LMP-7 inhibitor that covalently modifies proteasomal N-terminal threonine active sites. It inhibits growth and triggers apoptosis in multiple myeloma cells, demonstrating antitumor activities.
- Used as an experimental control
- Inhibits growth and triggers apoptosis in multiple myeloma cells
- Covalently modifies proteasomal N-terminal threonine active sites
- Acts as a selective tripeptide epoxyketone immunoproteasome subunit LMP-7 inhibitor
- Demonstrates antitumor activities
Sigma Aldrich Fine Chemicals Biosciences N-Butyl-N-(4-hydroxybutyl)nitrosamine ISOPAC(R), >=90% (GC) | 3817-11-6 | 1G
N-Butyl-N-(4-hydroxybutyl)nitrosamine ISOPAC(R), >=90% (GC) | Purity: >=90% (GC) | Mol Wt: 174.24 | 3817-11-6 | 1G
Medchemexpress LLC (R)-PR-924 | 98.5% | 618.72 | 25 MG
(R)-PR-924 is an isomer of PR-924 (HY-123587) and serves as an experimental control. PR-924 is a selective tripeptide epoxyketone immunoproteasome subunit LMP-7 inhibitor with an IC50 of 22 nM. It covalently modifies proteasomal N-terminal threonine active sites, inhibits growth, and triggers apoptosis in multiple myeloma (MM) cells, exhibiting antitumor activities.
- Serves as an experimental control
- Inhibits growth in multiple myeloma (MM) cells
- Triggers apoptosis in multiple myeloma (MM) cells
- Exhibits antitumor activities
- Covalently modifies proteasomal N-terminal threonine active sites
- Selective immunoproteasome subunit LMP-7 inhibitor
- IC50 of 22 nM for LMP-7 inhibition
Selleck Chemical LLC N-Nitrosodiethylamine-E0136-1G
N-Nitrosodiethylamine (N-Nitroso-diethylamine NDEA diethylnitrosamine DEN) is DNA reactive after bioactivation and produces tumors in many animal species N-Nitrosodiethylamine can be used to induce animal models of Lung Carcinoma
eMolecules Pharmablock / tert-butyl 2-phenylpiperazine-1-carboxylate / 25mg / 788479716 / PB07807 / 0.000 / 886766-60-5 / MFCD07367734 / 262.353 / C15H22N2O2
Pharmablock / tert-butyl 2-phenylpiperazine-1-carboxylate / 25mg / 788479716 / PB07807 / 0.000 / 886766-60-5 / MFCD07367734 / 262.353 / C15H22N2O2